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Sinclair Method Studies

This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.

Is Naltrexone and The Sinclair Method Available in Ireland?

Is Naltrexone and The Sinclair Method Available in Ireland?

Naltrexone is a prescription-only medication approved to help treat alcohol dependence in Ireland. It works by blocking the brain’s opioid receptors, reducing the sense of pleasure from alcohol. This dampens the reward cycle and gradually lessens alcohol cravings.

Gradual Reduction with The Sinclair Method: Why It Works

Gradual Reduction with The Sinclair Method: Why It Works

That’s where The Sinclair Method (TSM) shines. This innovative approach offers an alternative: gradual reduction, using the medication naltrexone to change your brain’s response to alcohol, one drink at a time.

Rethink Drink – Leading Providers of the Sinclair Method in the UK

Rethink Drink – Leading Providers of the Sinclair Method in the UK

At Rethink Drink, we're proud to be leading the charge in reshaping how the UK approaches alcohol recovery. For too long, individuals seeking change have faced limited choices: abstinence-only programmes, rigid systems, and shame-based narratives. We exist to offer a smarter, science-backed alternative — The Sinclair Method (TSM).

The Sunday Reset

Every Sunday, we share a 2-minute insight into the logic of the Sinclair Method.

Join thousands of others for our weekly newsletter and change how you see the problem,

because when you change the way you look at things, the things you look at change.

… There’s a reason we’re called Rethink Drink!

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